China’s Vaccine Adverse Reaction Data Released for the First Time

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Today, the China Centers for Disease Control and Prevention released on its official website the monitoring of adverse reactions to the new crown vaccination in China, from December 15, 2020 to April 30, 2021, in 31 provinces, autonomous regions, and municipalities directly under the Central Government. 

Among the adverse reactions, 26,078 were general , accounting for 82.96% of the total number of adverse reactions, and the reported incidence was 9.84 per 100,000 doses; 5356 cases of abnormal reactions, accounting for 17.04% of the total number of adverse reactions, and the reported incidence was 2.02 per 100,000 Dosage times: There are 188 severe cases, the reported incidence rate is 0.07/100,000 dose times, and the incidence rate is extremely rare (less than 1 in 10,000).

At the same time, the interpretation of the national adverse reaction monitoring information released by the China Center for Disease Control and Prevention shows that the general and abnormal reaction rates of China’s new coronavirus vaccine are lower than the average reported levels of other types of vaccines in China in 2019. Current assessments believe that the incidence of severe abnormal reactions is extremely low, and the benefits of vaccination against the new coronavirus far outweigh the risks. 

The main adverse reaction characteristics of the new coronavirus vaccine are basically similar to those reported by other vaccines. About 40% of subjective symptoms such as dizziness, fatigue, or nausea are reported in general reactions. Moderate and severe symptoms with objective measurement indicators such as fever, local redness, and induration are relatively rare. Symptoms are mostly transient, and they can subside after proper rest. . Among the abnormal reactions, allergic rash and angioedema have been reported in relatively large numbers, but they usually do not cause serious consequences. Acute severe allergic reactions such as anaphylactic shock and laryngeal edema are extremely rare and usually have no serious consequences after timely treatment.

Some countries have also reported the monitoring of adverse reactions after vaccination with the new coronavirus. Most of them also have systemic symptoms such as pain, redness and swelling at the injection site, fever, headache, nausea, diarrhea, fatigue, and limb pain. Individuals have also reported adverse events such as severe allergic reactions. After evaluation, it is deduced that , some severe allergic reactions may be related to the vaccine. Other events are still under continuous monitoring and research.

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